Biomineralization in zinc aluminate nanostructured ceramics
Abstract
In recent years, the nanomaterials have been proposed like a new option to increase the cellular response onto dental and orthopedic implants. With this in mind, it has been developed a study to investigate the effect of the nanotopography of one ceramic compound on the biomineralization process. In this case we use zinc aluminate films, deposited by spray pyrolysis technique, with nanometer sized morphologies. The obtained results, when culture osteoblastic cells onto nanoceramics, indicated that the nanometer sized surface of the proposed material increased the cellular adherence, as compared with the surfaces of the reference material. From the above-mentioned result, it can be deduced that the nanometer sized surface changes the properties of the ceramic material to behave as a material with
a bioactive surface. This bioactivity is manifested with the increment in the biomineralization of the extracellular matrix and in the orderly rise of the mineral tissue deposited. According to the obtained results,
we propose to the zinc aluminate films like a biocompatible ceramic which provides a similar nanometer sized ambient comparable with that of the human bone where biomineralization is favored. Such films can be applied on the implant materials in the dental and orthopedic area in our country.
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